The Department of Biotechnology (DBT) and Biotechnology Research and Innovation Council (BRIC) have launched the ‘One Day One Genome’ initiative, a transformative step to unlock India’s vast microbial potential. Announced on November 9, 2024, during BRIC’s first foundation day at the National Institute of Immunology (NII) in New Delhi, the initiative was introduced by Amitabh Kant, India’s G20 Sherpa and former CEO of NITI Aayog.
This groundbreaking program aims to spotlight India’s unique bacterial species and their critical roles in agriculture, environmental sustainability, and human health. Microorganisms, often termed the hidden champions of ecosystems, play crucial roles in biogeochemical cycles, soil fertility, and organic waste management. They not only assist in nutrient cycling and pest control in agriculture but also symbiotically enhance plant nutrient and water absorption. On a human level, they support digestion, immunity, and even mental health. Despite their significance, much of the microbial world remains unexplored.
Central to the initiative is genome sequencing, which will reveal the genetic blueprint of these microorganisms, showcasing their potential in producing essential enzymes, combating antimicrobial resistance, and creating bioactive compounds. This research holds immense promise for advancing environmental protection, boosting agricultural productivity, and improving human health outcomes.
The initiative is led by BRIC in collaboration with the National Institute of Biomedical Genomics (NIBMG), an institute under the DBT. It aims to release fully annotated bacterial genomes isolated within India, accompanied by comprehensive graphical summaries, infographics, and genome assembly details. These resources will be made publicly available, fostering scientific collaboration and community engagement.
The ‘One Day One Genome’ initiative promises to bridge the gap between science and society, driving innovations with real-world applications by making microbial genomics data accessible.
As microbial discoveries expand, the initiative is poised to stimulate discussions, inspire research, and yield benefits for the environment, agriculture, and public health.
